Description
Mast cells are versatile, tissue-homing secretory cells, which were first described by Paul Ehrlich in 1878. As most tumours contain inflammatory cell infiltrates, which often include plentiful mast cells, the question as to the possible contribution of mast cells to tumour development has progressively been emerged. Mast cells are versatile, tissue-homing secretory cells, which were first described by Paul Ehrlich in 1878. Mast cells have long been implicated in the pathogenesis of allergic reactions and certain protective responses to parasites. Their functional role, however, has been discovered to be increasingly complex and multifarious. Mast cells have been implicated in various cell-mediated immune reactions, being found in tissues from multiple disease sites, and as a component of the host reaction to bacteria, parasite, and even virus infections. They have also been shown to participate to angiogenic and tissue repair processes after injury. The importance of a possible functional link between chronic inflammation and cancer has long been recognized. As most tumours contain inflammatory cell infiltrates, which often include plentiful mast cells, the question as to the possible contribution of mast cells to tumour development has progressively been emerged. In this book, the general biology of these cells, their development, anatomical distribution and phenotype as well as their secretory products will first be discussed. The biology of tumour cells, their structural and molecular characteristics, the specificity of the tumour microenvironment and the development of a vascular network in the tumour context will be analyzed. The involvement of mast cells in tumour biology and tumour fate will then be considered, with particular emphasis on the capacity of these cells to stimulate tumour growth by promoting angiogenesis and lymphangiogenesis. The last chapter suggest that mast cells may serve as a novel therapeutic target for cancer treatment.
- Langue
- en
- Version
- Broché
- Date de sortie initiale
- 17 octobre 2014
- Nombre de pages
- 142
- Illustrations
- Non
Personnes impliquées
- Auteur principal
-
Domenico Ribatti
- Deuxième auteur
-
Enrico Crivellato
- Editeur principal
-
Springer
Informations sur le fabricant
- Nom du fabricant
- Springer Nature Customer Service Center GmbH
- Adresse du fabricant
- Europaplatz 3 | 69115| Heidelberg| DE
- Adresse électronique du fabricant
- ProductSafety@springernature.com
- Informations sur le fabricant
- Les informations du fabricant ne sont actuellement pas disponibles
Autres spécifications
- Hauteur de l’emballage
- 235 mm
- Largeur d’emballage
- 155 mm
- Largeur du produit
- 155 mm
- Livre d‘étude
- Oui
- Longueur d’emballage
- 235 mm
- Longueur du produit
- 235 mm
- Poids de l’emballage
- 244 g
- Police de caractères extra large
- Non
- Porno
- Non
- Édition
- 2011 ed.
EAN
- EAN
- 9789400794436
Sécurité des produits
- Opérateur économique responsable dans l’UE
-
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Vous trouverez cet article :
- Catégories
-
Science et nature
Médecine et Soins infirmiers
Médecine clinique et Interne
Médecine spécialisée
Biologie
Maladies et Troubles
Pathologie
Biologie cellulaire
Oncologie
Biologie spécialisée
Livres
- Livre, ebook ou livre audio ?
-
Livre
- Disponibilité
-
Disponible à l’adresse suivante
- Langue
-
Anglais
- Type de livre
-
Paperback
